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MMQ Cells

MMQ Cells
MMQ Cells
The MMQ cell line is a clonal, prolactin-secreting cell line derived from the 7315a rat pituitary tu...
13 213,00Kč
Cena bez DPH: 10 919,83Kč
  • Výrobce: Cytion
  • Kód výrobce: CYT-300498

Dostupné možnosti

Přidat do nabídky
Dotaz na zboží
The MMQ cell line is a clonal, prolactin-secreting cell line derived from the 7315a rat pituitary tumor. It exclusively secretes prolactin and expresses functional dopamine receptors, specifically of the D2 subtype. Dopamine inhibits prolactin (PRL) release by reducing intracellular cyclic AMP (cAMP) levels and calcium uptake, as demonstrated in various experiments. This inhibition is reversed by haloperidol and pertussis toxin, confirming the role of GTP-binding proteins in dopamine's action. MMQ cells are also responsive to somatostatin (SRIF) and vasoactive intestinal polypeptide (VIP), but not to TRH, angiotensin II, or neurotensin. MMQ cells proliferate rapidly, doubling in less than 24 hours under optimal conditions. When transplanted into rats, MMQ cells form tumors that increase serum prolactin levels without altering other hormones such as ACTH. This cell line is an important model for studying prolactin regulation, particularly in relation to dopamine and its inhibitory mechanisms on prolactin secretion. Rat cell lines, Brain, Rat pituitary gland neoplasm, Growth Conditions: Clusters in Suspension, Biosafety level: BSL 1
Technické specifikace
Doprava a skladování Clusters in Suspension
Poznámka k dopravě Dopravné k objednávce je závislé na BLS třídě dodávaných produktů a na konkrétních podmínkách přepravy. Před objednáním nás prosím kontaktujte a naši pracovníci Vám vždy cenu dopravy vyčíslí pro každý jednotlivý případ. Každá viála obsahuje celkem přibližně 3 miliony adherentních buněk nebo 5 milionů suspenzních buněk s typickou životaschopností po rozmrazení v rozmezí 80-95 %. Tyto údaje slouží jako obecné vodítko; ačkoli dodržujeme přísné normy kvality, přesné počty buněk a životaschopnost se mohou lot-to-lot lišit a nejsou zaručeny.
Vlastnosti
Aplikace 3D cell culture
Původ Rat
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